US Organ Preservation Market Demand was valued at USD 69.3 Mn. in 2023 and the total US Organ Preservation revenue is expected to grow at a CAGR of 3.9% from 2024 to 2030, reaching nearly USD 90.58 Mn.
Market Definition and Estimation
Organ preservation involves the removal, storage, and transportation of viable organs from donors to recipients, utilizing advanced techniques such as static cold storage, hypothermic machine perfusion, and normothermic machine perfusion. These methods maintain organ viability, temperature, and oxygenation, ensuring successful transplantation outcomes.
Market Growth Drivers and Opportunities
Several key factors are propelling the growth of the organ preservation market in the United States:
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Increasing Prevalence of Chronic Diseases: The rising incidence of chronic conditions such as diabetes, hypertension, and cardiovascular disorders has escalated the need for organ transplants. According to the Centers for Disease Control and Prevention (CDC), six in ten adults in the U.S. have a chronic disease, and four in ten have two or more, leading to over 106,000 individuals awaiting organ transplants.
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Technological Advancements: Innovations in preservation technologies, particularly normothermic machine perfusion, have significantly improved organ viability and transplant success rates. This technique outperforms traditional cold storage by extending organ viability, reducing wastage, and enhancing transplantation outcomes.
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Government Initiatives and Public Awareness: Government programs promoting organ donation, coupled with public awareness campaigns, have contributed to an increasing donor pool. Efforts to debunk myths surrounding organ donation encourage more registrations, expanding the availability of organs for transplantation.
Segmentation Analysis
The U.S. organ preservation market is segmented based on preservation solution, organ donation type, technique, organ type, and end user.
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By Preservation Solution:
- University of Wisconsin (UW) Solution: Widely used for preserving abdominal organs.
- Custodiol HTK: Preferred for cardiac and liver preservation.
- Perfadex: Commonly used for lung preservation.
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By Organ Donation Type:
- Living Organ Donation: Involves donors who are still alive, typically for kidney and liver transplants.
- Deceased Organ Donation: Accounts for a significant portion of organ transplants, with a 30% market share in 2023, driven by growing awareness and advancements in storage and logistics.
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By Technique:
- Static Cold Storage: Traditional method involving cooling organs to slow metabolism.
- Hypothermic Machine Perfusion: Circulates cold preservation solution through the organ to maintain viability.
- Normothermic Machine Perfusion: Maintains organs at body temperature, improving viability and reducing ischemic injury.
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By Organ Type:
- Kidney: High demand due to prevalent kidney diseases.
- Liver: Significant segment owing to liver disease incidence.
- Lung: Growing segment with advancements in preservation techniques.
- Heart: Critical segment with ongoing research to improve preservation methods.
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By End User:
- Hospitals and Clinics: Primary users of preservation solutions for transplantation procedures.
- Organ Banks: Specialized centers storing organs before transplantation.
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Competitive Landscape
The U.S. organ preservation market is characterized by the presence of several key players focusing on research and development to enhance preservation solutions and address challenges such as donor scarcity and logistical inefficiencies. Notable companies include:
- Xvivo Perfusion AB: Specializes in advanced perfusion systems to improve organ viability.
- Organ Recovery Systems: Develops innovative technologies for organ preservation and transportation.
- Waters Medical Systems: Offers solutions aimed at improving preservation outcomes.
- TransMedics, Inc.: Pioneers in portable organ perfusion systems, enhancing transplant success rates.
- Paragonix Technologies, Inc.: Provides advanced organ preservation devices to ensure optimal conditions during transport.
- Essential Pharmaceuticals, LLC: Offers products designed to improve organ preservation efficiency.
- OrganOx Limited: Develops normothermic machine perfusion devices to enhance liver preservation.
- Bridge to Life Ltd.: Focuses on developing preservation solutions to improve transplant outcomes.
- 21st Century Medicine, Inc.: Engages in cryopreservation technologies for organ preservation.
Conclusion
The United States organ preservation market is poised for steady growth, driven by the increasing prevalence of chronic diseases, technological advancements in preservation methods, and supportive government initiatives promoting organ donation. Addressing ethical and logistical challenges will be critical in ensuring equitable access to life-saving transplants while fostering innovation in preservation techniques.
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