Overview De novo genome assembly is the process of splicing DNA fragments into contiguous segments (overlapping clusters) representing the chromosomes of an organism. Accurate, complete and contiguous genome assemblies are essential for identifying important structural and functional elements of the genome and for recognizing genetic variation. However, the short read lengths produced...

Overview Nanopore sequencing is a rapidly maturing length-based sequencing technology capable of analyzing natural DNA/RNA and sequencing fragments of any length, from short to ultra-long, making it possible to elucidate all types of genetic and epigenetic variation. However, while this technology has improved in recent years, it still exhibits relatively high error rates on raw sequences...