In the base Diablo 2, end-game builds revolved around certain unique weapons and armor. D2R Ladder Items gave players something else to farm for, not only the runes themselves but the perfect pieces in which to fit them. The most coveted runes can also be used as currency in trading for the best items. In this guide, you will konw how to use runes and how to farm runes. What are Diablo 2...